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However, research has demonstrated that deleting the C/EBPβ leucine zipper domain not only halts dimerization and DNA binding but also augments ubiquitination and proteasomal degradation of C/EBPβ ( In vitro studies have shown that ST101 promotes G0–G1 phase arrest and dose-dependent cell death in various tumor cell lines, including PCa cells, without affecting normal human immune cells ( 6 Conclusion PCa remains a significant global health concern, with ADT and immunotherapy facing limitations in effectively treating the disease, especially in its advanced stages
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