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Additionally, chemokines regulate the migration patterns of T CM and T EM cell subsets, ensuring efficient immune surveillance and the establishment of robust immunological memory at mucosal barriers ( In this review, we focus on the physiological roles of the major mucosal-specific chemokines CXCL17, CCL25, CCL28, and CXCL14 in shaping CD4 + and CD8 + T RM cell-mediated immunity to mucosal infectious diseases ( Figure 1 and Table 1 )