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The preclinical literature includes findings involving: Tendon healing Ligament injury Muscle injury Bone injury Inflammatory models Gastrointestinal tissue Vascular responses These findings help explain why BPC-157 is being investigated, but they should not be interpreted as proof that BPC-157 is an established treatment for chronic pain
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Mechanistically, NO2-FAs covalently modify STING through nitro-alkylation of Cys88 and Cys91, which abrogates STING palmitoylation inhibiting STING signaling (183)
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