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In a 1988 study by Maquart, Pickart, and colleagues, GHK-Cu stimulated collagen synthesis in cultured fibroblasts at concentrations as low as 10⁻¹² M, with peak effect at 10⁻⁹ M, independent of changes in cell number
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It is sometimes used as a skin-lightening agent, as it can inhibit the production of melanin (the pigment that gives skin its colour) and improve skin complexion
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