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Within controlled laboratory settings, 5-Amino-1MQ is utilized to study how NNMT inhibition alters intracellular nicotinamide handling and affects downstream metabolic signaling pathways, including those related to NAD+ homeostasis, mitochondrial dynamics, and adipocyte functionality
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10.1210/en.2002-0143 [DOI] [PubMed] [Google Scholar] Fukunaga K., Tsutsumi H., Mihara H
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