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Therefore, in this review, the term potential biomarkers will be used to encompass all these findings, ranging from well-established biomarkers like PSA or PCA3 to emerging ones that are currently being studied, not only as susceptibility biomarkers but also in other areas like prognosis or treatment selection (34, 35)
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A genetic screen was performed using the Matchmaker Gold Y2H system (Clontech) to generate cnd1 mutations that disrupt the Cnd1-Pmc4 interaction without affecting the Cnd1-Cnd2 interaction between the condensin subunits
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