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Metformin-Induced Vitamin B12 Deficiency in Patients with Type 2 Diabetes: A Narrative Review with a Practical Approach for Screening, Diagnosing, and Managing Vitamin B12 Deficiency
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Where methyl wins on the evidence: people with known MTHFR variants that affect methylation pathways, anyone with neurological symptoms or peripheral neuropathy, and people who have poor conversion efficiency (which can be tested but rarely is in clinical practice)
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