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Cell-culture work has reported effects on collagen and glycosaminoglycan synthesis, fibroblast activity and antioxidant behaviour, and rodent studies have reported faster closure in experimental wound and burn models, with one frequently cited rodent burn study reporting roughly a 33% increase in healing rate
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The physiologic role of LAL may therefore lead to eventual inhibition of LAL activity in the presence of excess atherogenic lipoprotein uptake, contributing further to the progression of atherosclerosis
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