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Neuroinflammation In a 2021 review, researchers explain that urolithin A “attenuates inflammation in various tissues.” Though most of the reviewed studies have been done using mice, urolithin A “consistently” inhibited neuroinflammation, leading researchers to suggest the compound could be beneficial in mediating certain effects of neurodegenerative diseases.28 And the Alzheimer’s Drug Discovery Foundation even supports its use early in treatment.4 Skin aging Most of the research on urolithin A products for skin health was conducted by Amazentis SA, the creator of Mitopure and the owner of Timeline

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Furthermore, a recent study determined that NNMT and 1-MNA regulated autophagy through the ROS-mediated AMPK pathway, protecting breast cancer cells from oxidative stress (71)