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Changes to the gut microbiota during dysbiosis have now been linked to a myriad of diseases such as IBD, irritable bowel syndrome (IBS), obesity and rheumatoid arthritis [118–121]
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10 In the 1960s, scientists gradually elucidated the specific steps of methionine metabolism, revealing that methionine enters the methylation pathway via SAM, is then converted to Hcy through SAH, and subsequently re-enters the methionine cycle through remethylation reactions
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