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The percentage of the anorexigenic effect on the experimental day was calculated by subtracting the observed to the basal intake and then dividing the result by observed intake, by the following formula [29–31]: Dose-response curves were constructed by plotting the % of anorexigenic effect against the tesofensine or 5-HCP/CB administered individually, and ED30 (+ SEM) values were estimated by linear regression

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No regulatory body — Health Canada, the FDA, the EMA, the TGA, or any equivalent — has approved 5-Amino-1MQ as a drug for human or veterinary use