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Cardiovascular disease In cardiovascular disease, Myc and Myc-related factor X (Max) upregulate the Gln transporters SLC1A5 and SLC7A5 and mitochondrial malate in pulmonary hypertension, thereby promoting glutaminolysis-induced right ventricular hypertrophy
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Lipid peroxidation in AD patients’ brain tissues has been demonstrated, with increased activity of lipid peroxidation enzymes such as 12/15-LOX and ACSL4 and elevated levels of highly reactive secondary products like MDA detected in certain brain regions (Praticò et al., 2004
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