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Structural basis of the activation of type 1 insulin-like growth factor receptor | Nature Communications
To identify when mitochondrial therapies should be administered and to confirm mitochondrial engagement, assessing mitochondrial function in patients, through cardiac biopsies, measures of cellular energetics, or circulating biomarkers such as lactate/pyruvate ratios, will be crucial [164]
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When any of these pathways are blocked, homocysteine levels can rise, which causes negative long-term health effects
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